Why we’re watching this show: House returns this season with more smart-aleck comments from House (Hugh Laurie) and many more patients with a variety of conditions.

The last season finale ended with House imagining he and Dr. Cuddy (Lisa Edelstein) had had sex and that she obviously has feelings for him. In reality, what he remembered did not even happen.

After shouting out the false comment of the two of them having sex in an attempt to get her to admit her true feelings, Cuddy fires him only to find that after his medical detox, he is truly not OK. House is then admitted into a mental institute.

The two-hour season premiere will air on Monday, Sept. 21 at 8 p.m. ET.  

• Stacie Bailey